T-cell immunotherapies
T-cell receptor (TCR) T-cell therapy: continuing the revolution of immunotherapy
The past few decades have seen remarkable innovations in cancer immunotherapy, which harnesses the immune system to fight tumors, yet unmet needs remain.1-3 Cellular immunotherapy approaches, such as TCR T-cell therapies, are one avenue undergoing continued research to help address remaining unmet needs for patients with solid tumors.3
APC=antigen-presenting cell; CD=cluster of differentiation.
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Overview of T-cell therapies for solid tumors
References
- Riley RS, June CH, Langer R, Mitchell MJ. Delivery technologies for cancer immunotherapy. Nat Rev Drug Discov. 2019;18(3):175-196.
- Stanculeanu DL, Daniela Z, Lazescu A, Bunghez R, Anghel R. Development of new immunotherapy treatments in different cancer types. J Med Life. 2016;9(3):240-248.
- Rohaan MW, Wilgenhof S, Haanen JBAG. Adoptive cellular therapies: the current landscape. Virchows Arch. 2019;474(4):449-461.